When the sense of kinesthesia, the vestibular system, and visual cues do not agree, motion sickness may result. Susceptibility to motion sickness varies greatly from one person to another. Motion sickness presents itself as a generally uncomfortable feeling, nausea, or even vomiting. A person with motion sickness often feels dizzy, becoming pale and sweating.

These feelings result from the disagreement of the motion sensing systems in the brain. Avoiding turbulence, minimizing head movements, and flying as gently as possible will minimize the intensity of confusing information coming in from the person's sense of kinesthesia and vestibular system. Since the brain prefers visual cues over the other motion sensing systems, keep the person with motion sickness looking outside. Pointing out an interesting landmark or tasking the passenger to look for something outside can provide visual cues and reduce anxiety by taking their mind off of the motion sickness. Getting some fresh air flowing through the cabin usually helps the passenger feel more comfortable, as well.